[4-[(Dimethylamino)carbonyl]-3-fluorophenyl]boronic acid - Names and Identifiers
[4-[(Dimethylamino)carbonyl]-3-fluorophenyl]boronic acid - Physico-chemical Properties
Molecular Formula | C9H11BFNO3
|
Molar Mass | 211 |
Density | 1.28 |
Melting Point | 147-149 |
Boling Point | 418.8±55.0 °C(Predicted) |
Flash Point | 207.1°C |
Vapor Presure | 9.21E-08mmHg at 25°C |
pKa | 6.67±0.10(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.535 |
[4-[(Dimethylamino)carbonyl]-3-fluorophenyl]boronic acid - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Hazard Note | Irritant/Keep Cold |
[4-[(Dimethylamino)carbonyl]-3-fluorophenyl]boronic acid - Introduction
[4-(dimethylcarbamoyl)-3-fluoro-phenyl]boronic acid is an organic compound whose chemical formula is C9H11BFNO2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline solid
-melting point: about 110-112 ℃
-Solubility: Slightly soluble in water, soluble in some organic solvents such as ethanol and dimethylformamide
-Stability: Stable under normal temperature and pressure conditions
Use:
- [4-(dimethylcarbamoyl)-3-fluoro-phenyl]boronic acid is an important intermediate in organic synthesis and is commonly used in organic synthesis reactions.
-It can be used as an alkylating agent for aromatic compounds and as a chelating agent.
-In the field of drug development, pesticide synthesis and materials science has a wide range of applications.
Preparation Method:
A common method for preparing this compound is to react 3-fluorophenylboronic acid with dimethylformamide. Detailed synthetic methods can be found in the relevant professional literature or patents.
Safety Information:
- [4-(dimethylcarbamoyl)-3-fluoro-phenyl]boronic acid is generally considered a relatively safe compound.
-Care should be taken when handling appropriate personal protective equipment, such as laboratory gloves and protective glasses.
-Avoid direct contact with skin and inhalation of dust from the compound.
-In the event of accidental inhalation or exposure to the compound, wash the affected area immediately and seek medical advice.
Last Update:2024-04-09 02:00:48